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π CustomizeMedical Overview of Striate Palmoplantar Keratoderma
Sources citedStriate palmoplantar keratoderma is an isolated, focal, hereditary palmoplantar keratoderma characterized by linear hyperkeratosis along the flexor aspect of the fingers and on palms, as well as focal hyperkeratosis of the plantar skin. Patients present with painful thickening of the skin on palms and soles, with occasional fissuring, blistering and hyperhidrosis. Rarely, hyperkeratosis on other areas may be seen (knees, dorsal aspects of the digits). Histopatologically, widened intercellular spaces between keratinocytes are observed.
Classification & codes: GARD 0015016 · Orphanet ORPHA:50942 · OMIM 148700 · ICD-10 Q82.8
Sources: GARD (NIH/NCATS), Orphanet Β· last reviewed 2026. Educational only β not medical advice.
News & Updates
ALYFTREK shows positive Phase 3 results in children ages 2β5
Vertex plans global regulatory submissions for this pediatric age group in the first half of 2026.
Airway clearance routines that actually work for teens

3 open trials match this profile
Locations in NC, FL and GA.
Striate Palmoplantar Keratoderma Family Conference
Illustrative example event Β· location TBD
Care & management overview — Striate Palmoplantar Keratoderma
Educational programming; see the cited sources on this hub.
Striate Palmoplantar Keratoderma News & Developments
The latest Striate Palmoplantar Keratoderma research, news and registered trials — live from public sources. Each link opens the source directly; nothing here is auto-summarized or invented.
Recruiting trials
View all →Find a Striate Palmoplantar Keratoderma Specialist Near You
Sample results β illustrative only. A real version would search the NPPES provider registry and CFF-certified centers by actual distance from your ZIP.
Treatment & Daily Living
Medical care plus the everyday therapies and supports relevant to Striate Palmoplantar Keratoderma. Treatment is individualized — ask your specialist about the medications, procedures and therapies. Browse medications →
Media Center
News, podcasts, books & research for Striate Palmoplantar Keratoderma — real coverage, links out, never re-hosted.
Audience Guides
Plain-language guidance for the people around someone with Striate Palmoplantar Keratoderma — how to understand it and talk about it. AI-generated for communication, not medical advice; always confirm specifics with a clinician.
Companies Developing Treatments
Biopharma companies with registered trials for Striate Palmoplantar Keratoderma — from ClinicalTrials.gov. Informational, not an endorsement, and not every program is in trials.
Preferences only β saved to your account, never shared or sold. No PHI. Sources: GARD (NIH/NCATS), Orphanet.
Tools
Every institution behind the faculty, with their affiliated experts.
Plain-language tools
For clinicians, nonprofits & industry partners.
Translates any dense medical text β papers, lab results, visit notes, jargon β into plain language.
Live on tomekohealth.com β not a demo mock-up.
Research Collaboration & Matching
Live on tomekohealth.com β not a demo mock-up.
Mental Health Toolkit
Sources citedCoping strategies, how to find a a specialist therapist, and mental-health resources built for the ups and downs of living with Striate Palmoplantar Keratoderma β for patients and caregivers alike.
Preferences only β saved to your account, never shared or sold. No PHI. Sources: GARD (NIH/NCATS), Orphanet.
Grand Rounds & Accredited Education
Open Questions
Ask the community βAnyone can ask. Sign in to answer. Peer support — not medical advice, and no PHI.
Survey
Reflect on how you are doing β anonymous, with only de-identified group averages shown.
Community & Support Groups
For people living with Striate Palmoplantar Keratoderma. Peer support, not medical advice; no PHI.
For caregivers and family navigating Striate Palmoplantar Keratoderma.
Recent From the Community
Certified Centers of Excellence
CFF networkCare centers and specialists for Striate Palmoplantar Keratoderma, from Tomeko’s verified provider directory (CMS NPPES).
Representative CFF centers β the official CFF directory has the complete, current list.
Nonprofits & Foundations
Grants & Financial Help
Representative programs β illustrative only. Eligibility and availability vary; not a guarantee of assistance.
Patient & Family Guides
Sources citedAn annual snapshot of Striate Palmoplantar Keratoderma research, treatment access and outcomes, written in plain language for patients and families.
Practical starting points and things to plan for in the first year after diagnosis.
Step-by-step guidance, what to expect, and a sample daily routine.
Disclosure, accommodations, insurance transitions and workplace planning for teens and young adults with Striate Palmoplantar Keratoderma.
Sources: GARD (NIH/NCATS), Orphanet Β· last reviewed 2026. Educational only β not medical advice.