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🔗 CustomizeMedical Overview of Charcot-Marie-Tooth Disease Dominant Intermediate E
Sources citedA rare hereditary motor and sensory neuropathy disorder characterized by the typical CMT phenotype (slowly progressive distal muscle weakness and atrophy in upper and lower limbs, distal sensory loss in extremities, reduced or absent deep tendon reflexes and foot deformities) associated with focal segmental glomerulosclerosis (manifesting with proteinuria and progression to end-stage renal disease). Mild or moderate sensorineural hearing loss may also be associated. Nerve biopsy reveals both axonal and demyelinating changes and nerve conduction velocities vary from the demyelinating to axonal range (typically between 25-50m/sec).
Classification & codes: GARD 0012011 · Orphanet ORPHA:93114 · OMIM 614455 · ICD-10 G60.0
Sources: GARD (NIH/NCATS), Orphanet · last reviewed 2026. Educational only — not medical advice.
News & Updates
ALYFTREK shows positive Phase 3 results in children ages 2–5
Vertex plans global regulatory submissions for this pediatric age group in the first half of 2026.
Airway clearance routines that actually work for teens
3 open trials match this profile
Locations in NC, FL and GA.
Charcot-Marie-Tooth Disease Dominant Intermediate E Family Conference
Illustrative example event · location TBD
Care & management overview — Charcot-Marie-Tooth Disease Dominant Intermediate E
Educational programming; see the cited sources on this hub.
Charcot-Marie-Tooth Disease Dominant Intermediate E News & Developments
The latest Charcot-Marie-Tooth Disease Dominant Intermediate E research, news and registered trials — live from public sources. Each link opens the source directly; nothing here is auto-summarized or invented.
Recruiting trials
View all →Find a Charcot-Marie-Tooth Disease Dominant Intermediate E Specialist Near You
Sample results — illustrative only. A real version would search the NPPES provider registry and CFF-certified centers by actual distance from your ZIP.
Treatment & Daily Living
Medical care plus the everyday therapies and supports relevant to Charcot-Marie-Tooth Disease Dominant Intermediate E. Treatment is individualized — ask your specialist about the medications, procedures and therapies. Browse medications →
Media Center
News, podcasts, books & research for Charcot-Marie-Tooth Disease Dominant Intermediate E — real coverage, links out, never re-hosted.
Audience Guides
Plain-language guidance for the people around someone with Charcot-Marie-Tooth Disease Dominant Intermediate E — how to understand it and talk about it. AI-generated for communication, not medical advice; always confirm specifics with a clinician.
Companies Developing Treatments
Biopharma companies with registered trials for Charcot-Marie-Tooth Disease Dominant Intermediate E — from ClinicalTrials.gov. Informational, not an endorsement, and not every program is in trials.
Preferences only — saved to your account, never shared or sold. No PHI. Sources: GARD (NIH/NCATS), Orphanet.
Tools
Every institution behind the faculty, with their affiliated experts.
Plain-language tools
For clinicians, nonprofits & industry partners.
Translates any dense medical text — papers, lab results, visit notes, jargon — into plain language.
Live on tomekohealth.com — not a demo mock-up.
Research Collaboration & Matching
Live on tomekohealth.com — not a demo mock-up.
Mental Health Toolkit
Sources citedCoping strategies, how to find a a specialist therapist, and mental-health resources built for the ups and downs of living with Charcot-Marie-Tooth Disease Dominant Intermediate E — for patients and caregivers alike.
Preferences only — saved to your account, never shared or sold. No PHI. Sources: GARD (NIH/NCATS), Orphanet.
Grand Rounds & Accredited Education
Open Questions
Ask the community →Anyone can ask. Sign in to answer. Peer support — not medical advice, and no PHI.
Survey
Reflect on how you are doing — anonymous, with only de-identified group averages shown.
Community & Support Groups
For people living with Charcot-Marie-Tooth Disease Dominant Intermediate E. Peer support, not medical advice; no PHI.
For caregivers and family navigating Charcot-Marie-Tooth Disease Dominant Intermediate E.
Recent From the Community
Certified Centers of Excellence
CFF networkCare centers and specialists for Charcot-Marie-Tooth Disease Dominant Intermediate E, from Tomeko’s verified provider directory (CMS NPPES).
Representative CFF centers — the official CFF directory has the complete, current list.
Nonprofits & Foundations
Grants & Financial Help
Representative programs — illustrative only. Eligibility and availability vary; not a guarantee of assistance.
Patient & Family Guides
Sources citedAn annual snapshot of Charcot-Marie-Tooth Disease Dominant Intermediate E research, treatment access and outcomes, written in plain language for patients and families.
Practical starting points and things to plan for in the first year after diagnosis.
Step-by-step guidance, what to expect, and a sample daily routine.
Disclosure, accommodations, insurance transitions and workplace planning for teens and young adults with CMTDIE.
Sources: GARD (NIH/NCATS), Orphanet · last reviewed 2026. Educational only — not medical advice.